Strategic adaptability and an entrepreneurial orientation (EO) are commonly depicted as desirable organizational qualities. This paper explores the relationship between strategic adaptability and EO as well as the moderating effect of structure-style fit on this relationship. Data collected from 110 manufacturing firms indicate that strategic adaptability is weakly related to EO. However, firms that exhibit greater alignment between their organization structures and top management decision-making styles tend to have more positive strategic adaptability-EO relationships.