The current study investigated the relationship between the psychological capital and work tension of entrepreneurs on their level of job satisfaction using a national (United States) random sample of 144 founders who were the top management team leaders of their new ventures. As expected, the findings demonstrate a positive relationship between psychological capital and job satisfaction and a negative relationship between work tension and job satisfaction. Also in alignment with our predictions, psychological capital was found to reduce the negative effects of work tension on job satisfaction. As such, it appears that the development of psychological capital within entrepreneurs may help them to build resistance against the wide range of psychological stressors that they inherently face while leading their new ventures.