The creation and management of new businesses can create both positive and negative outcomes for entrepreneurs. In particular, the demands of a new business may stress the link between the entrepreneur’s family and work domains, and thereby create conflict within the entrepreneur. This conflict, which is termed work and family conflict (Burke & Greenglass, 1987), can hinder the psychological health of the entrepreneur and subsequently affect the performance of the new firm. Whether the conflict is related to family demands that inhibit attention to business needs, or work demands that affect family processes, work and family is particularly relevant to family businesses (Neubauer & Lank, 1998). The current study considers the relationships between work and family conflict on important psychological outcomes, namely work tension and satisfaction. These relationships are examined for entrepreneurs of family and non-family firms, with the goal of clarifying the theoretical relationships between these constructs.