This research focuses on the evolution of a corporate radical innovation management system in the context of two different of economic systems and business cultures: Korea and the U.S. In particular to what extent do key elements of a corporate business system (strategy, process, customer, and employee) influence the development of a radical innovation management system; and further, to what extent do characteristics of corporate entrepreneurs (proactiveness, risk-taking, autonomy, and aggressiveness) influence the engagement of these four key elements of a corporate business system? The firm’s corporate entrepreneurship capacity may vary as a function of the types of corporate entrepreneurship characteristics embodied in the firms’ corporate entrepreneurs; the extent to which they are encouraged or discouraged; and the extent to which they are developed to influence the engagement of the key elements of a firm’s business system.