Using a multilevel analysis, we explore the gender—innovation activity relationship. We investigate founder education, inter-firm network ties, and firm regional location as mediators using a sample of 4,265 new Korean firms. Results show that male founders, compared to female, are more likely to complete engineering or natural science degrees, maintain heterogeneous inter firm network ties, and locate firms in clustered regions. Further, engineering or natural science degrees, heterogeneous inter-firm network ties, and locating in clustered regions are positively associated with innovation activity. We find evidence that each of these multilevel constructs mediate the relationship between entrepreneur gender and innovation activity.