There has been a growing interest in understanding gender issues in academic entrepreneurship. In this study we focus on the incubator context and how related institutional structures work in relation to women’s entry into academic entrepreneurship. The principal question is to what extent structural characteristics in the entrepreneurial eco-system surrounding incubators influence the likelihood that women may engage in the commercialization of university science by becoming incubatees. Theoretically, we embed our arguments in institutional theory and develop hypotheses related to (1) the share of female faculty at the closest university, (2) gender norms in the primary industry of the new venture project, and (3) the prior experience of the incubator in dealing with women incubatees.