This study explores the effects of a natural disaster in the context of attitudes, activities and aspirations towards entrepreneurship. Our study relies on data gathered before and after the earthquake that took place in Chile on February 27th, 2010. Evidence shows that the impact of a natural disaster on entrepreneurs’ expectations and perceptions could be as relevant as the direct consequences of material destruction. The earthquake triggered changes in social capital, because such an event shapes new relationships, increasing the number of ties among entrepreneurs. These new relationships not only generate variation in entrepreneurial activity, but also on entrepreneurial attitudes and aspirations.