The authors develop a comprehensive framework to improve understanding of the complex causalities and interdependencies of the factors affecting the scalability of social impact. Examining the entire literature on scaling social enterprises and nonprofits, they single out 241 key drivers for scalability and 144 scaling strategies, then group the key drivers into coding categories and condense them into clusters. From these clusters, one precondition and seven key components are derived for scaling social impact. The 144 strategies are sorted into four types. By interlinking the precondition, key components, and strategy types, the framework responds to several calls in recent literature.