Disinhibition is a broad construct from psychology involving weak cognitive and behavioral inhibition. While most literature focuses on the negative aspects of disinhibition, it may facilitate nascent entrepreneurial behavior. This paper appears the first to empirically and theoretically link the two. Disinhibition, or relatively weaker cognitive and behavioral inhibition, has been associated with a variety of adverse outcomes – from poor job performance and work-place deviance (e.g. Hogan & Holland, 2003; Diefendorff & Mehta, 2007), to substance abuse and clinical disorders (Sher & Trull, 1994; Nigg, 2000). Yet disinhibition and associated sensation seeking or impulsivity can also be productive (e.g. van den Boss et al., 2009; Carver, 2005; Dickman, 1990). Entrepreneurship requires individuals uninhibited by established protocol, willing to act under uncertainty and with limited planning (e.g. Schumpeter, 1934; Busenitz & Barney, 1997). As disinhibition addresses key aspects of cognition, motivation, and behavior in concert – it reflects the complexity of reality while offering parsimony to theorists and empirical researchers.