We analyze differences between intrapreneurs and entrepreneurs regarding persistence and speed in their nascent start-up efforts. Despite established research that compares intrapreneurs and entrepreneurs (Weiss, 1981; Zahra, 1996; McDougall, Robinson Jr, & DeNisi, 1992; Shrader & Simon, 1997) and recent findings on the persistence of entrepreneurs (Holland & Shepherd, 2013; DeTienne, Shepherd, & Castro, 2008; Gatewood, Shaver, Powers, & Gartner, 2002), it remains less clear how the venturing mode (independent entrepreneur or intrapreneur) influences persistence and expeditious market entry in the earliest venturing stages. Understanding how entrepreneurs and intrapreneurs differ in speed and persistence helps interpreting findings based on existing ventures and set managerial expectations. It also contributes to the discussion on organizational impact on new venture creation. We offer theoretical explanations concerning differences in resource endowments, imprinting effects, embeddedness, legitimacy concerns and bureaucracy that influence both groups in their nascent venturing phase.