Work-life balance (WLB) is in the central debate of quality of life. Some scholars argue that self- employment might be a panacea for a WLB, but it also can be a double-edged sword (Prottas and Thompson, 2006): entrepreneurs still struggle with combining work and other responsibilities in life. Different work characteristics of entrepreneurs might influence their capabilities to achieve WLB because implies opportunities but also several constraints that shape and affect people’s capabilities to combine work and life domains (Hobson, 2013), but also national context can influence (Reynolds et al., 2005). The aims of this article are 1) to test the influence of individual work characteristics and 2) to test the (interaction) effect of a country’s culture on the entrepreneurs’ abilities to maintain WLB. We analyze these data from capabilities and agency theory adapted for WLB (Hobson, 2013).