The decision to pursue an entrepreneurial path can be facilitated by supportive environments, or ecosystems (Lee and Peterson, 2000; Toledano and Urbano, 2008). An ecosystem is defined as an agglomeration of interconnected individuals, entities, and governance bodies in a given geographic area that collectively support entrepreneurial activity (Malecki, 2011). University students interested in starting their own new ventures are naturally embedded in two different ecosystems, that of their family (Habbershon, 2006) and that of their university (Fetters, Greene, & Rice, 2010). In this study, we look at the differential effect of family and university support on the start-up activities of young men and women nascent entrepreneurs.