Entrepreneurial intentions have been identified as the single most powerful predictor of new venture creation, but the way to positively influence those intentions has been debated in the literature. Some research has validated that entrepreneurship education has a positive effect on intention, and other findings suggest that intentions can be increased by improving self-efficacy perceptions. However, there has been limited consideration of how specific traits play a role in that process. This research aims to investigate the impact of personal-level variables on entrepreneurial self-efficacy perceptions and intentions for male and female adolescents with dyslexia, whom studies have shown exhibit lower levels of self-esteem. It also highlights areas in entrepreneurship education that might increase entrepreneurial self-efficacy perceptions and intention in that audience.